A case of synchronous mucinous metaplasia and neoplasia of the female genital tract without an STK11 or KRAS mutation☆
نویسندگان
چکیده
► Synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN-FGT) is a rare mucinous lesion. ► This is the first case of SMMN-FGT with DNA sequencing of STK11 and KRAS, but no mutation was identified.
منابع مشابه
Synchronous mucinous metaplasia and neoplasia of the female genital tract with external urethral meatus neoplasm: A case report
•We present a case of multiple mucinous metaplasia and neoplasia of cervix, endometrium, fallopian tube, ovary, and mesenterium with external urethral meatus neoplasm.•Immunohistochemistry showed almost same pattern in each neoplasms.•PCR-direct sequencing showed no existence of both KRAS and GNAS mutations.•This report suggests a possibility of synchronous mucinous metaplasia and neoplasia "be...
متن کاملColorectal and Vulvar Synchronous Cancer: A Case Report
Synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. Globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. Vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...
متن کاملFemale genital tract tumors and gastrointestinal lesions in the Peutz-Jeghers syndrome.
BACKGROUND Peutz-Jeghers Syndrome (PJS) is a rare genetic disorder characterized by mucocutaneous melanin deposition, and intestinal hamartomatous polyps, with an increased risk of breast, gastrointestinal, and female genital tract cancers. CASE REPORT Multiple genital tract neoplasms in a 52-year-old northern Thai woman with PJS are described. The patient presented with abdominal distention....
متن کاملSynchronous mucinous cystadenoma ovary, leiomyoma uterus and mucinous adenocarcinoma cervix infiltrating into uterine leiomyoma: a rare case report
The synchronous or metachronous occurrance of multiple primary cancers in the genital tract is well recognized. The overall incidence of synchronous female genital tract malignancies is 0.63%. The most frequently observed synchronous neoplasms are those of the ovary together with the endometrium. These constitute 40% of all, and carry a favourable prognosis because of low malignant potential. C...
متن کاملPeutz-Jeghers Syndrome with Multiple Genital Tract Tumors and Breast Cancer: A Case Report with a Review of Literatures
We report here on the multiple genital tract neoplasms in a 41-yr-old Korean woman with Peutz-Jeghers Syndrome (PJS). The patient presented with lower abdominal pain. Her previous medical history was PJS and breast cancer. Pelvic ultrasound showed a multilocular cyst at the right adnexal region, diagnosed as bilateral ovarian mucinous borderline tumors. An ovarian sex cord tumor with annular tu...
متن کامل